Approach to child with chronic or recurrent cough
Objectives
To know
– the right questions to ask
– age-related differentials and investigating appropriately
– how to manage the child with chronic cough using a systematic approach
Outline
Definition
Mechanism/ phases of cough
Classification
Asking the right questions
Age-related differentials
Investigating the child
Managing the child
Definition
Cough – common indication of respiratory illness and is one main symptom of children seeking medical attention
It is an explosive expiration that provides a normal protective mechanism for clearing the tracheobronchial tree of secretions and foreign material.
Mechanism of cough

Expiratory phase: opening of the glottis results in high expiratory flow and audible coughs. During this phase, the airway undergoes dynamic compression and the expulsion of air facilitates airway debris and secretions clearance.

HOW DO WE NARROW OUR DIAGNOSIS WHILE APPROACHING A CHILD WITH COUGH

GOOD HISTORY
Onset; Productive; Character; Variation
• Onset
sudden -after choking episode- foreign body, with feeds – GERD,
With ETS exposure
recurrent- atopic type,
chronic- TB, bronchiectasis
• Productive
older children with early morning severe expectoration- Bronchiectasis,
non- productive and only when awake- habitual; -asthma
• Variation
nocturnal and early morning- atopic type, seasonal – hay fever/asthma
lying down- GERD, postural – bronchiectasis, postnasal drip, cardiac
• Character/timing/associated factors
– Barking- croup,
spasmodic- atopic type
Whoop, sounds, stridor, voice change, fever
GOOD PHYSICAL EXAMINATION
Blood shot eye, clubbing
AGE MATTERS…….

The child’s age is a key guide

The child’s age is a key guide.
In another study, persistent bacterial bronchitis (PBB), post-infectious causes, and bronchiectasis accounted for a combined 68% of cases.
In the 2 reviews involving older children, the corresponding totals for these 3 diagnoses were 5% and 40% (the latter included PBB, 35%), respectively.
Investigating the child….

Managing chronic cough – an algorithm

Specific diseases that cause cough
PBB
TB
PERTUSIS
ASTHMA/ABPA
CF
GERD
PCD
CSLD
FB
Nutritional/environmental/health education/life style modification
IN SUMMARY – remember
– the right questions to ask
– age-related differentials and how to investigate appropriately
– how to manage the child with chronic cough using a systematic approach
REFERENCES
1. Goldsobel AB, Chipps BE. Cough in the pediatric population. J Pediatr. 2010;156(3):352-358.
2. Munyard P, Bush A. How much coughing is normal? Arch Dis Child. 1996;74(6):531-534.
3. Chang AB, Glomb WB. Guidelines for evaluating chronic cough in pediatrics: ACCP evidence-based clinical practice guidelines. Chest. 2006;129(1 suppl):260S-283S.
4. Khoshoo V, Edell D, Mohnot S, Haydel R Jr, Saturno E, Kobernick A. Associated factors in children with chronic cough. Chest. 2009;136(3):811-815.
5. Asilsoy S, Bayram E, Agin H, et al. Evaluation of chronic cough in children. Chest. 2008;134(6):1122-1128.
6. Marchant JM, Masters IB, Taylor SM, Cox NC, Seymour GJ, Chang AB. Evaluation and outcome of young children with chronic cough. Chest. 2006;129(5):1132-1141.
7. Mayo Clinic. Childhood asthma. Available at: http://www.mayoclinic.org/diseases-conditions/childhood-asthma/basics/symptoms/con-20028628. Published March 5, 2013. Accessed February 13, 2015.
8. Guilbert TW, Morgan WJ, Zeiger RS, et al. Atopic characteristics of children with recurrent wheezing at high risk for the development of childhood asthma. J Allergy Clin Immunol. 2004;114(6):1282-1287.
9. Marchant JM, Gibson PG, Grissell TV, Timmins NL, Masters IB, Chang AB. Prospective assessment of protracted bacterial bronchitis: airway inflammation and innate immune activation. Pediatr Pulmonol. 2008;43(11):1092-1099.
10. Irwin RS, Baumann MH, Bolser DC, et al: American College of Chest Physicians (ACCP). Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest. 2006;129(1 suppl):1S-23S.
11. Marchant JM, Masters IB, Taylor SM, Chang AB. Utility of signs and symptoms of chronic cough in predicting specific cause in children. Thorax. 2006;61(6):694-698.
12. Brooke AM, Lambert PC, Burton PR, Clarke C, Luyt DK, Simpson H. Recurrent cough: natural history and significance in infancy and early childhood. Pediatr Pulmonol. 1998;26(4):256-261.
13. Carter ER, Debley JS, Redding GR. Chronic productive cough in school children: prevalence and associations with asthma and environmental tobacco smoke exposure. Cough. 2006;2:11.
14. Chang AB, Redding GJ, Everard ML. Chronic wet cough: protracted bronchitis, chronic suppurative lung disease and bronchiectasis. Pediatr Pulmonol. 2008;43(6):519-531.
15. Chipps B. What should I do with that child with a chronic cough?: A problem-based learning approach. Presented at: American Academy of Pediatrics 2014 National Conference and Exhibition, October 11-14, 2014; San Diego, California.